Rupatadine is a long-acting, non-sedative antagonist of histamine H1-receptors. It also antagonizes the platelet-activating factor (PAF). Both histamine and PAF cause bronchoconstriction which leads to an increase in vascular permeability and acts as a mediator in the inflammatory process. With the dual mode of action, Rupatadine shows a better therapeutic effect than an isolated antihistamine. …
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